TAKEDA-SPONSORED
Gastroenterology Scientific Presentations
Presented at Digestive Disease Week
May 2 – May 5, 2026 | Chicago, IL
Inflammatory Bowel Disease (IBD)
POSTER #Sa1561
Influence of social determinants of health on advanced therapy initiation in patients with inflammatory bowel diseases in the US
Brown J, Sindaco M, Munshi K, Imeri H, Gravlee E, Barfield E, Siegel CA (presenting author)
Health Disparities
May 2, 2026
12:30 PM – 1:30 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2
POSTER #Su1627
Efficacy and safety of intravenous vedolizumab in pediatric patients with moderate-to-severe ulcerative colitis: Results from the KEPLER Phase 3 trial
Turner D, Kierkus J, Korczowski B, Strisciuglio C, Chen J, Takaki Y, Szakos E, Arumugam R (presenting author), Rizvi A, Yoon M, Campagne O, Angellotti E, Candela N, Velazco N
Uncontrolled Trials and Observations: Biologics
May 3, 2026
12:30 PM – 1:30 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2
POSTER #Su1639
Dual targeted therapy with vedolizumab and tofacitinib in patients with ulcerative colitis: Initial results from the Phase 4 ExiGem study
Yarur A (presenting author), Deepak P, Barnes EL, Ha C, Hudesman D, Jairath V, Lukin DJ, Rubin DT, Schreiber S, Gower M, Jones S, Robinson I, Sanchirico M, Yajnik V
Uncontrolled Trials and Observations: Biologics
May 3, 2026
12:30 PM – 1:30 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2
POSTER #Su1644
Persistence and treatment patterns of patients with inflammatory bowel disease switching from vedolizumab intravenous to subcutaneous maintenance therapy: Data from a Canadian cohort
Horst SN (presenting author), Moulson R, Yang Z, Pettengell C, Brown J, Barfield E, Gift T, Liu Y, Power GS, Bressler B
Uncontrolled Trials and Observations: Biologics
May 3, 2026
12:30 PM – 1:30 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2
POSTER #Mo1517
Evaluation of transmural healing in patients with moderately to severely active Crohn's disease shows early efficacy of vedolizumab: VECTORS Week 14 interim analysis
Jairath V (presenting author), Vuyyuru SK, Ma C, Zou GY, Neustifter B, Agboton C, Romo Bautista I, Wu JJ, Jiang J, Allocca M, An Y-K, Begun J, Bryant RV, Danese S, Dubinsky M, Freire M, Novak KL, Panaccione R, Pudipeddi A, Rubin DT, Sands BE, Sparrow M, Taylor SA, Gecse K, Maaser C, Feagan BG, Wilkens R
Controlled Clinical Trials of IBD Treatment
May 4, 2026
12:30 PM – 1:30 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2
POSTER #Mo1510
Molecular and cellular signatures accompanying early disease clearance in ulcerative colitis patients treated with vedolizumab in the VERDICT trial
Mehandru S (presenting author), Powell N, Silverberg M, Peyrin-Biroulet L, Hernandez Rocha C, Colombel JF, D’Haens G, Moran GW, Sebastian S, Travis S, Filice M, Massimino L, Picard J, Sangiorgi B, Shackelton LM, Smith MI, Teft W, Arunachalam V, Agboton C, Farahmand S, Freire M, Paraskevopoulou M, Panchal P, Wan Y-W, Feagan BG, Jairath V
Omics, Spatial and Systems Biology I
May 4, 2026
12:30 PM – 1:30 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2
POSTER #Mo1475
Gut inflammatory monocytes as biomarkers of treatment response to TYK2 inhibition in inflammatory bowel disease
Onabajo O (presenting author), Tang J, Creed H, Hornsby E, Wyrobnik I, Cogan A, Wilson E, Sherlock J, Wennbo H, Heap G, Arunachalam V, Choudhury A, Lindsay JO, Stagg A
Immune and Non-Immune Cells in Intestinal Inflammation
May 4, 2026
12:30 PM – 1:30 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2
POSTER #Tu1465
Zasocitinib (TAK-279), an investigational oral, allosteric, highly selective and potent TYK2 inhibitor preserves anti-inflammatory IL-10 signaling in vitro
Orlandi C (presenting author), Lin K-Y, Kumar S, Sherlock J, Wilson E, Petrakis I, Salas A
Mechanisms of IBD Therapeutics
May 5, 2026
12:30 PM – 1:30 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2
POSTER #Tu1487
Molecular characterization of responders to vedolizumab identified by symptom response trajectories, study endpoints, and mucosal gene transcriptomic analyses
Paraskevopoulou M (presenting author), Farahmand S, Hou R, Cheng J, Panchal P, Agboton C, Candela N, Yajnik V, Dulai PS, Schreiber S, Thakker P
Omics, Spatial and Systems Biology II
May 5, 2026
12:30 PM – 1:30 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2
POSTER #Tu1494
Machine learning-based stratification to define distinct disease trajectories following advanced therapy initiation in Crohn’s disease and ulcerative colitis
Xiong X, Cai E, Panickan V, Morini Sweet S, Wanchaitanawong W, Duan R, Chou C, Brown J, Sanchirico M, Hughes G, Cai T, Ananthakrishnan A (presenting author)
AI Applications in IBD
May 5, 2026
12:30 PM – 1:30 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2
POSTER #Tu1495
Machine-learning based stratification identifies treatment trajectory subtypes and unmet need in inflammatory bowel diseases
Xiong X, Cai E, Panickan V, Morini Sweet S, Wanchaitanawong W, Duan R, Chou C, Brown J, Sanchirico M, Hughes G, Cai T, Ananthakrishnan A (presenting author)
AI Applications in IBD
May 5, 2026
12:30 PM – 1:30 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2
POSTER #Tu1496
Reclassification and assessment of patients with inflammatory bowel disease: A large language model-based framework for disease activity tracking and trajectory modeling in routine practice
Lin Z (presenting author), Rosas L, Chou C, Brown J, Sanchirico M, Hanauer SB, Luo Y, Dulai PS
AI Applications in IBD
May 5, 2026
12:30 PM – 1:30 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2
Eosinophilic Esophagitis (EoE)
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POSTER #Tu1106
Real-world experiences with treatments for eosinophilic esophagitis (EoE) in the USA: Qualitative results from interviews with patients and healthcare professionals
Low EE, Goodwin B, Khoja L, Lloyd J, Houpt B, Daniel I, Schaeffer-Koziol C, Terreri B, Gonsalves N (presenting author)
Eosinophilic Esophagitis: Treatment
May 5, 2026
12:30 PM – 1:30 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2
POSTER #Tu1098
Treatment patterns in patients with eosinophilic esophagitis (EoE) in the USA treated with budesonide oral suspension, off-label corticosteroids and dupilumab
Sauer B (presenting author), McGowan EC, Lam F, Silber A, Goodwin B, Khoja L, Schaeffer-Koziol C, Terreri B, Moawad FJ
Eosinophilic Esophagitis: Treatment
May 5, 2026
12:30 PM – 1:30 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2
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POSTER #Tu1104
Patients receiving budesonide oral suspension (BOS) in real-world practice have more severe eosinophilic esophagitis (EoE) at baseline than those not receiving BOS: Results from a retrospective cohort study using US health insurance claims data
Dellon ES (presenting author), Goodwin B, Lee L, Korgaonkar S, Meyers J, Schaeffer-Koziol C, Terreri B, Shah E
Eosinophilic Esophagitis: Treatment
May 5, 2026
12:30 PM – 1:30 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2
Short Bowel Syndrome
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POSTER #Su1792
Healthcare resource utilization for adults and children with short bowel syndrome-associated intestinal failure identified from ICD-10-CM codes: Real-world US claims analysis
Buchman AL (presenting author), Goodwin B, Iyer KR, Lam F, Liu Y, Mercer DF, Silber A, Terreri B, Tappenden K
Intestinal Failure and Short Gut
May 3, 2026
12:30 PM – 1:30 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2
Celiac Disease
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POSTER #Sa1254
Meaningful symptom change in celiac disease: Qualitative findings from an exit interview study following a Phase 2 clinical trial
Ghura S (presenting author), Harris N, Arvizu M, Leffler DA
Celiac Disease I
May 2, 2026
12:30 PM – 1:30 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2
POSTER #Sa1253
Psychometric validation of the Celiac Disease Symptom Diary v2.1 using data from a Phase 2 study in patients with moderate to severe celiac disease
Ghura S (presenting author), Rockwood N, Tahir M, Arvizu M, McLeod L, Leffler DA
Celiac Disease I
May 2, 2026
12:30 PM – 1:30 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2
POSTER #Sa1255
Symptom severity and inadvertent gluten exposure among patients with celiac disease
Arvizu M, Marden J, Sethi S, Cheinquer N, Saad R, Ghura S (presenting author), Canavan J, Liu E, Adams DMW, Geller M
Celiac Disease I
May 2, 2026
12:30 PM – 1:30 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2
ePOSTER #146
Risk of eating disorders in patients with celiac disease and their first-degree relatives: A nationwide population-based cohort study
Yao J (presenting author), Sun J, Bergman D, Mårild K, Liu S, Green PHR, Arvizu M, Bulik CM, Lebwohl B, Ludvigsson J
Small Intestine ePoster Showcase
May 2, 2026
1:15 PM – 1:45 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2
ORAL PRESENTATION #1003
Assessing histologic change in serial celiac duodenal biopsies using routine pathology practices: Factors affecting accuracy and interobserver reliability
Robert M (presenting author), Chen ZE, Pacheco C, Goldsmith J, Gonzalez RS, Pai R, Panarelli N, Lagana SM, Arnold M, Wilkins B, Karamchandani DM
Clinical Insights in Celiac Disease
May 5, 2026
8:00 AM – 9:30 AM CT
McCormick Place - W195
ORAL PRESENTATION #1098
TG2 inhibition during gluten reintroduction skews duodenal immunometabolism toward omega-3/linoleic pathways and ferroptosis control in celiac disease
Pesi A (presenting author), Dotsenko V, Isola J, Taavela J, Mohrbacher R, Mueller R, Tewes B, Mäki M, Viiri K, Schuppan D
Celiac Disease: Mechanisms and Endpoints
May 5, 2026
10:00 AM – 11:30 AM CT
McCormick Place - W184d
ORAL PRESENTATION #1099
Continuous composite scoring histologic and biomarker indicators for celiac disease
Syage JA (presenting author), Maxwell J, Lavin PT, Fremgaard Risnes L, Lundin KEA, Sollid LM
Celiac Disease: Mechanisms and Endpoints
May 5, 2026
10:00 AM – 11:30 AM CT
McCormick Place - W184d
Gastroesophageal reflux disease (GERD)
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POSTER #Tu1223
Efficacy of potassium-competitive acid blocker (PCAB)-based therapies for Helicobacter pylori infection: A network meta-analysis of randomized controlled trials
Mi C, Zhou K, Shi Y, Liang K, Zhou F, Song Z (presenting author)
Helicobacter pylori: Treatment, Antimicrobial Resistance
May 5, 2026
12:30 PM – 1:30 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2
POSTER #Tu1165
Effectiveness and safety of vonoprazan in elderly Chinese patients with gastroesophageal reflux disease: A post hoc analysis of the multicentre, prospective, VIEW study
Xiao Y, Wang B, Xu L, Liang K (presenting author), Zhou F, Chen M
GERD: Medical Treatment
May 5, 2026
12:30 PM – 1:30 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2
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POSTER #Tu1168
Effectiveness of vonoprazan on symptom relief in gastroesophageal reflux disease patients with anxiety or depression in China: Post hoc analysis of the VIEW study
Xiao Y, Hou X, Zhang D, Liang K (presenting author), Zhou F, Chen M
GERD: Medical Treatment
May 5, 2026
12:30 PM – 1:30 PM CT
McCormick Place - Poster Hall, Level 3, Hall F2